Serum protein electrophoresis interpretation pdf

Onedimensional protein electrophoresis separates the proteins in serum or urine into their main classes albu min and alpha, beta and gamma globulins on. In other cases, patients may have nonspecific symptoms, meaning the discovery is. Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. An immunofixation tutorial protein serum electrophoresis. Clinical use and interpretation of serum protein electrophoresis and. The subsets of these proteins and their relative quantity are the primary focus of the interpretation of serum protein electrophoresis. Protein electrophoresis with interpretation, serum. Understanding and interpreting the serum protein electrophoresis. The total serum protein test measures all the proteins in your blood.

Serum protein electrophoresis is a laboratory examination that commonly is used to identify patients with multiple myeloma and other disorders of serum protein. Serum protein electrophoresis an overview sciencedirect topics. Serum protein bands monoclonal gammopathy will sometimes be found following serum protein electrophoresis in patients. Serum protein electrophoresis spep is a widely available and inexpensive laboratory test that examines specific serum proteins based on their physical properties. Abnormal serum protein electrophoresis pattern in a. The most important aspect of such albumin variants lies in quantification of an albumin peak in such scenarios followed by interpretation and clinical correlation. Making sense of serum protein bands serum protein bands monoclonal gammopathy will sometimes be found following serum protein electrophoresis in patients presenting with classic signs or symptoms of multiple myeloma, e. Pdf serum protein electrophoresis is used in clinical practice to identify. Hemoglobin is the protein inside red blood cells responsible. Electrophoresis separates proteins based on their physical properties, and the subsets of these proteins are used in interpreting the results. Serum protein electrophoresis and its clinical applications. Serum protein electrophoresis spep is an easy, inexpensive method of separating proteins based on their net charge, size, and shape. Understanding and interpreting serum protein electrophoresis.

Serum protein electrophoresis spep is a laboratory technique thats used to determine the level of some types of proteins in a blood sample. Dubois lupus erythematosus and related syndromes eigth edition, 20. The serum protein electrophoresis procedure is intended for the separation and quantitation of serum proteins using cellulose acetate electrophoresis. Common problems associated with the interpretation of serum protein electrophoresis are summarized in box 7. It can also check the amount of albumin you have compared to globulin, or whats called your ag ratio. Serum protein electrophoresis separates serum proteins into the following. Serum protein electrophoresis is used to identify patients with. Labcorp test details for protein electrophoresis with interpretation, serum with reflex to ife, serum, and free. In some cases, additional time should be allowed for additional. The subsets of these proteins and their relative quantity are serum protein electrophoresis is used to identify patients with multiple myeloma and other serum protein disorders. An immunofixation tutorial presented by john okeefe sha robinson, phd rita. Understanding and interpreting serum protein electrophoresis csv. Two major types of proteins can be identified with.